反应详情

温度

150 °C

A mixture of 1,3-dioxo-1H,3H-benzo[de]isochromene-5-carboxamide (0.5 mmol), 4-Aminobutyric acid (1.5 mmol) and 4 mL ethanol was heated to 150° C. for 30 minutes in microwave reactor (Biotage, Initiator). The reaction mixture was cooled to room temperature and the cream color precipitate was collected by filtration and washed with ethanol. The final product was dried in vacuum for 24 hours to give desired compound.

1. temperatureThe reaction mixture was cooled to room temperature
2. filtrationthe cream color precipitate was collected by filtration
3. washwashed with ethanol
4. dry with materialThe final product was dried in vacuum for 24 hours