Acetone → HCID 59752533, compound

HRID 2106219Notes

Reaction equation

[CH2:1]([N:8]1[C:17]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12][C:11]=2[C:10]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:24][C:25]([CH3:27])=O>>[CH2:1]([N:8]1[C:17]2[CH2:16][CH2:15][N:14]([CH:25]([CH3:27])[CH3:24])[CH2:13][CH2:12][C:11]=2[C:10]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[N:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 180Acetone

HCID 59752508HCID 59752508, compound

Product 1

HCID 59752533HCID 59752533, compound

Procedure

The title compound (0.03 g) was prepared from 1-benzyl-3-phenyl-1,4,5,6,7,8-hexahydro-1,2,6-triaza-azulene (Example 44, 0.07 g) and 22 μL of acetone as in Example 35. MS (ESI): exact mass calculated for C23H27N3, 345.22; found, m/z 346.3 [M+H]+. 1H NMR (500 MHz, CD3OD): 7.57-7.52 (m, 2H), 7.50-7.27 (m, 6H), 7.22-7.20 (m, 2H), 5.47 (s, 2H), 3.77-3.61 (m, 3H), 3.29-3.28 (m, 3H), 3.24-3.08 (m, 3H), 1.40 (d, J=6.0 Hz, 6H).

Sources & evidence

ORD record: ord-96086b8b84a34e259e5991f7b8f58bc2
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07579470B2

Reaction notes

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