Methanol → (1S,2R)-(+)-Norephedrine

HRID 210630Notes

Reaction equation

HRID 210630 reaction equation
[CH3:19][OH:20].[c:1]1([CH:7]([CH:8]([CH3:9])[NH:10][C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[OH:18])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH:8]([CH3:9])[NH2:10])[OH:18])[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 887MethanolHCID 541439tert-butyl N-(1-hydroxy-1-phenylpropan-2-yl)carbamate

Product 1

HCID 4786(1S,2R)-(+)-Norephedrine

Sources & evidence

ORD record
ord-77cdf1d900d246c08c49420942e40e77
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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