Ethanol → N-Methyl-N-[(3S,4S)-4-methyl-3-piperidyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

HRID 210640Notes

Reaction equation

HRID 210640 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([N:15]([c:16]2[c:17]3[c:18]([n:19][cH:20][n:21]2)[nH:22][cH:23][cH:24]3)[CH3:25])[CH:11]([CH3:14])[CH2:12][CH2:13]1.[CH3:28][CH2:29][OH:30].[H:26][H:27].[OH-:31].[OH-:33].[Pd+2:32]>>[NH:8]1[CH2:9][CH:10]([N:15]([c:16]2[c:17]3[c:18]([n:19][cH:20][n:21]2)[nH:22][cH:23][cH:24]3)[CH3:25])[CH:11]([CH3:14])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 702EthanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 12084829N-(1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amineHCID 178418361HCID 178418361, compound

Product 1

HCID 12084830N-Methyl-N-[(3S,4S)-4-methyl-3-piperidyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-c718880813404e9a87af3d28f91b76ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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