HCID 86600678, compound → HCID 86600680, compound

Participants

Reaction Steps

A mixture of 0.29 g 1-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranos-1-yl)4-methyl-3-[4-(trimethylsilylethynyl)-benzyl]-benzene and 0.25 g of 10% palladium hydroxide on charcoal in 3 ml of ethyl acetate is shaken for 24 h at ambient temperature under a hydrogen pressure of 1 atm. Then another 0.2 g of catalyst are added and the solution is shaken for a further 20 h under a hydrogen atmosphere. Then the catalyst is filtered off, the filtrate is evaporated down and the residue is chromatographed through silica gel (dichloromethane/methanol 1:0->5:1).

Provenance & Evidence