Sodium borohydride → HCID 11443332, compound

Participants

Reaction Steps

A solution of [(2-{1-[4-(3,3-dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethylpropyl}-benzofuran-5-carbonyl)-amino]-acetic acid (74 mg, 0.150 mmol) in THF (5.0 mL) at RT is treated with NaBH4 (11 mg, 0.300 mmol). The resulting mixture is stirred for 4 hour. The reaction is quenched with HCl (1.0 N, 1.0 mL) and extracted with EtOAc (2×20 mL). The organic layer is dried over Na2SO4, concentrated to afford the title compound (65 mg, 88%).

Provenance & Evidence