1,2-Dichloroethane → HCID 11432640, compound

Participants

Reaction Steps

2-{1-[4-(2-tert-butyl-[1,3]dioxolan-2-ylmethoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzofuran-5-carboxylic acid (125 mg, 0.260 mmol), EDC (75 mg, 0.391 mmol), DMAP (95 mg, 0.781 mmol), and glycine methyl ester hydrochloride (49 mg, 0.39 mmol) are reacted to produce the intermediate followed by hydrolysis analogous to Example 1, step K to give title compound (125 mg, 90%).

Provenance & Evidence