HCID 57810545, compound → HCID 57810593, compound

Participants

Reaction Steps

A solution of 1-{4-[1-(6-benzyloxy-benzofuran-2-yl)-1-ethyl-propyl]-2-methyl-phenoxy}-3,3-dimethyl-butan-2-one (5.90 g, 11.8 mmol) in EtOAc (20.0 mL) is added a slurry of Pd—C (590 mg, 10%) in MeOH (20.0 mL) at RT. The resulting mixture is stirred under hydrogen balloon pressure for 2 h. The mixture is filtered through a pad of celite and the filtrate is concentrated, the residue is purified with 20-30% EtOAc/Hex to afford the title compound (4.35 g, 90%).

Provenance & Evidence