Sodium borohydride → HCID 11305195, compound

Participants

Reaction Steps

A solution of 2-{1-[4-(3,3-dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzofuran-6-carboxylic acid (110 mg, 0.252 mmol) in THF (5.0 mL) at RT is treated with NaBH4 (19 mg, 0.505 mmol). The resulting mixture is stirred for 1 h and is quenched with water (1.0 mL) and extracted with EtOAc (3×30 mL). The organic layer is dried over Na2SO4, concentrated to afford the title compound (105 mg, 95%).

Provenance & Evidence