HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dichloroethane → HCID 11477108, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Dimethylamine, hydrochloride | HCID 10473 | — |
| Reactant | HCID 11316880 | HCID 11316880 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 11477108 | HCID 11477108 | 98% |
Reaction Steps
5-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-7-methyl-benzofuran-2-carboxylic acid (270 mg, 0.599 mmol) in CH2Cl2 (10 mL) and DMAP (220 mg, 1.80 mmol), EDC (172 mg, 0.898 mmol), and dimethyl amine hydrochloride (73 mg, 0.90 mmol) are reacted analogous to Example 5 to yield title compound (280 mg, 98%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579488B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-08bf5c2cd961408398e1fad884e4b93f |
| Source note | uspto-grants-2009_08 |