1,2-Dichloroethane → HCID 11156676, compound

Participants

Reaction Steps

5-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-7-methyl-benzofuran-2-carboxylic acid (720 mg, 1.60 mmol) in CH2Cl2 (10 mL) and DMAP (586 mg, 4.80 mmol) and EDC (460 mg, 2.40 mmol) are reacted with sarcosine ethyl ester hydrochloride (368 mg, 2.40 mmol) and the intermediate ester is hydrolyzed analogous to Example 7 to yield title compound (610 mg, 73%). MS (ES) m/e: 520.3 (M−1), 522.3 (M+1)

Provenance & Evidence