HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → HCID 68814100, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | HCID 76618000 | HCID 76618000 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 68814100 | HCID 68814100 | 77% |
Reaction Steps
4-(1-Ethyl-propenyl)-2-hydroxy-benzaldehyde (9.00 g, 47.3 mmol) and ethyl bromoacetate (9.88 g, 59.1 mmol) and K2CO3 (13.1 g, 94.6 mmol) in acetone (100 mL) followed by DBU (mL) and DMF (40 mL) are reacted analogous to Example 30-B to give the title compound (9.40 g, 77%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579488B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-da4b9696340141bc96b5673957a3e518 |
| Source note | uspto-grants-2009_08 |