HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 57810558, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Ethyl N-methylaminoacetate hydrochloride | HCID 171173 | — |
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 11305195 | HCID 11305195 | — |
| Product | HCID 57810558 | HCID 57810558 | — |
Reaction Steps
2-{1-Ethyl-1-[4-(2-hydroxy-3,3-dimethyl-butoxy)-3-methyl-phenyl]-propyl}-benzofuran-6-carboxylic acid (115 mg, 0.262 mmol), HATU (142 mg, 0.376 mmol), DIEA (0.3 ml, 1.02 mmol), and sarcosine ethyl ester hydrochloride (48 mg, 0.314 mmol) are reacted followed by base hydrolysis with 2N NaOH in an analogous manner to example 59 from to yield (66 mg, 25%) MS (ES) m/e: 508.2 (M−1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579488B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-d79ff5e8b36748f79588bb6b6a45a1dc |
| Source note | uspto-grants-2009_08 |