Sodium Hydroxide → HCID 57810539, compound

Participants

Reaction Steps

2-{1-Ethyl-1-[4-(2-hydroxy-3,3-dimethyl-butoxy)-3-methyl-phenyl]-propyl}-benzofuran-5-carboxylic acid (152 mg, 346 mmol) HATU (145 mg, 380 mmol) DIEA (0.35 ml, 2.07 mmol) and sarcosine ethyl ester hydrochloride (63 mg, 0.415 mmol) are reacted followed by base hydrolysis with 2N NaOH in an analogous manner to example E from to yield (78 mg, 56%). MS (ES) m/e: 508.3 (M−1)

Provenance & Evidence