1,2-Dichloroethane → HCID 57810570, compound

Participants

Reaction Steps

A solution of 5-{1-[4-(3,3-Dimethyl-2-oxo-cyclohexyloxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzofuran-2-carboxylic acid (153 mg, 0.331 mmol) (from example R2), EDC (94 mg, 0.496 mmol), HOBT (47 mg, 0.347 mmol), triethylamine (0.2 ml, 1.3 mmol), and sarcosine ethyl ester hydrochloride (76 mg, 0.496 mmol) were reacted followed by base hydrolysis as in Example 74 to yield (55 mg, 34%) MS (ES) m/e: 532.3 (M−1)

Provenance & Evidence