Potassium Hydroxide → HCID 15016262, compound

HRID 2106585Notes

Reaction equation

HRID 2106585 reaction equation
C([O:3][C:4]([CH:6]([O:8][C:9]1[N:13]=[CH:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([F:23])([F:22])[F:21])[CH:15]=2)[N:10]=1)[CH3:7])=[O:5])C.[OH-].[K+]>C(O)C>[C:4]([CH:6]([O:8][C:9]1[N:13]=[CH:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([C:20]([F:23])([F:21])[F:22])[CH:15]=2)[N:10]=1)[CH3:7])([OH:5])=[O:3]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 184260Ethyl 2-({1-[3-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-3-yl}oxy)propanoate

Product 1

HCID 15016262HCID 15016262, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Fifteen g of the compound of Example 3 was refluxed for 3 hours with 5.1 g of potassium hydroxide in 150 ml of ethanol, and the product was collected as shown in Example 22 and recrystallized from ethanol to obtain 11.8 g of the desired product, m.p. 206°-208°.

Workup

  1. customthe product was collected
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-3a57debc47f446f996ed5971742f3a4b
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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