Potassium Hydroxide → HCID 15016263, compound

HRID 2106586Notes

Reaction equation

HRID 2106586 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][C:10]([O:13][CH:14]([C:16]([O:18]CC)=[O:17])[CH3:15])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[OH-].[K+]>C(O)C>[C:16]([CH:14]([O:13][C:10]1[N:11]=[CH:12][N:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:9]=1)[CH3:15])([OH:18])=[O:17]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 184261Ethyl 2-{[1-(3-chlorophenyl)-1H-1,2,4-triazol-3-yl]oxy}propanoate

Product 1

HCID 15016263HCID 15016263, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 6.7 g portion of the compound of Example 5 was refluxed for 3 hours with 2.5 g of potassium hydroxide in 100 ml of ethanol and the product was collected as shown in Example 22 and recrystallized from ethanol to obtain 5.2 g of the desired product, m.p. 197°-199°.

Workup

  1. customthe product was collected
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-1b732a435bfb40c3874e331702c2ecd3
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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