Potassium Hydroxide → HCID 15016265, compound

HRID 2106588Notes

Reaction equation

HRID 2106588 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[N:11][C:10]([O:13][CH:14]([C:16]([O:18]CC)=[O:17])[CH3:15])=[N:9]2)=[CH:4][CH:3]=1.[OH-].[K+]>C(O)C>[C:16]([CH:14]([O:13][C:10]1[N:11]=[CH:12][N:8]([C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[N:9]=1)[CH3:15])([OH:18])=[O:17]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 163820Ethyl 2-{[1-(4-chlorophenyl)-1H-1,2,4-triazol-3-yl]oxy}propanoate

Product 1

HCID 15016265HCID 15016265, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Three g of the compound of Example 12 was refluxed for 2 hours with 1.1 g of potassium hydroxide in 100 ml of ethanol, and the product was collected as shown in Example 22 and was recrystallized from ethyl acetate to obtain 1.9 g of the desired product, m.p. 196°-198°.

Workup

  1. customthe product was collected
  2. customwas recrystallized from ethyl acetate

Sources & evidence

ORD record
ord-732cfb054329404aa343e7161fcf445b
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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