Potassium Hydroxide → HCID 54375287, compound

HRID 2106593Notes

Reaction equation

HRID 2106593 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([CH3:13])=[N:11][C:10]([O:14][CH:15]([C:17]([O:19]CC)=[O:18])[CH3:16])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[OH-].[K+]>C(O)C>[C:17]([CH:15]([O:14][C:10]1[N:11]=[C:12]([CH3:13])[N:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[N:9]=1)[CH3:16])([OH:19])=[O:18]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 163821Ethyl 2-{[1-(3-chlorophenyl)-5-methyl-1H-1,2,4-triazol-3-yl]oxy}propanoate

Product 1

HCID 54375287HCID 54375287, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 3.8 g portion of the compound of Example 17 was refluxed for 4 hours with 1.4 g of potassium hydroxide in 100 ml of ethanol, and the product was collected as shown in Example 22 and recrystallized from ethanol to obtain 2.8 g of the desired product, m.p. 101°-103°.

Workup

  1. customthe product was collected
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-b9cd3c313b59421b98ba547d9f94536a
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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