Potassium Hydroxide → HCID 15016275, compound

HRID 2106594Notes

Reaction equation

HRID 2106594 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[N:11][C:10]([O:13][CH:14]([C:16]([O:18]CC)=[O:17])[CH3:15])=[N:9]2)=[CH:4][CH:3]=1.[OH-].[K+]>C(O)C>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[N:11][C:10]([O:13][CH:14]([C:16]([OH:18])=[O:17])[CH3:15])=[N:9]2)=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 15016258HCID 15016258, compound

Product 1

HCID 15016275HCID 15016275, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ten g of the compound of Example 19 was refluxed for 10 minutes with 3.3 g of potassium hydroxide in 150 ml of ethanol, and the product was collected as described in Example 22 and recrystallized from ethanol to obtain 8.0 g of the desired product, m.p. 195°-197°.

Workup

  1. customthe product was collected
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-3b02bc9ea60e443e954abd0cfab15071
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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