Potassium Hydroxide → HCID 15016276, compound

HRID 2106595Notes

Reaction equation

HRID 2106595 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][C:10]([O:13][CH:14]([C:16]([O:18]CC)=[O:17])[CH3:15])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[OH-].[K+]>C(O)C>[Br:1][C:2]1[CH:3]=[C:4]([N:8]2[CH:12]=[N:11][C:10]([O:13][CH:14]([C:16]([OH:18])=[O:17])[CH3:15])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 15016259HCID 15016259, compound

Product 1

HCID 15016276HCID 15016276, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 28.8 g portion of the compound of Example 20 was refluxed for 10 minutes with 9.5 g of potassium hydroxide in 100 ml of ethanol, and the product was collected as shown in Example 22 and recrystallized from ethanol to obtain 21.6 g of the desired product, m.p. 198°-200°.

Workup

  1. customthe product was collected
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-ae63b7536e2f4e26b4c13972a30cbcaa
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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