Potassium Hydroxide → HCID 15016300, compound

HRID 2106618Notes

Reaction equation

C([O:3][C:4]([CH:6]([O:8][C:9]1[N:13]=[CH:12][N:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=2)[N:10]=1)[CH3:7])=[O:5])C.[OH-].[K+]>>[C:4]([CH:6]([O:8][C:9]1[N:13]=[CH:12][N:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:21])[F:22])=[CH:16][CH:15]=2)[N:10]=1)[CH3:7])([OH:5])=[O:3]

Participants

Reactant 2

HCID 14797Potassium Hydroxide

HCID 15016299HCID 15016299, compound

Product 1

HCID 15016300HCID 15016300, compound

Procedure

A 17.1 g portion of the compound of Example 64, prepared in successive reactions, was hydrolyzed with 5.8 g of potassium hydroxide, substantially as shown in Example 58, to obtain 15.5 g of the desired product, m.p. 215°-218°.

Sources & evidence

ORD record: ord-b3f417420f684dd3b79793885b85b653
Source dataset: uspto-grants-1990_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04931083

Reaction notes

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