Ethylamine → HCID 23048828, compound

HRID 2106650Notes

Reaction equation

HRID 2106650 reaction equation
O=[C:2]([C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][CH2:17][N:18]2[CH2:23][CH2:22][N:21]([C:24]3[CH:29]=[CH:28][CH:27]=[C:26]([C:30]([F:33])([F:32])[F:31])[CH:25]=3)[CH2:20][CH2:19]2)=[CH:10][CH:9]=1)[CH2:3][CH2:4][C:5](O)=[O:6].[CH2:34]([NH2:36])[CH3:35]>>[CH2:34]([N:36]1[CH:2]([C:8]2[CH:9]=[CH:10][C:11]([CH2:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:23][CH2:22][N:21]([C:24]4[CH:29]=[CH:28][CH:27]=[C:26]([C:30]([F:31])([F:33])[F:32])[CH:25]=4)[CH2:20][CH2:19]3)=[CH:12][CH:13]=2)[CH2:3][CH2:4][C:5]1=[O:6])[CH3:35]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 14423684HCID 14423684, compound

Product 1

HCID 23048828HCID 23048828, compound

Procedure

4-Oxo-4-[4-(4-(4-(3-trifluoromethylphenyl)piperazin-1-yl)butyl)phenyl]butyric acid and ethylamine are reacted together to give N-ethyl-5-[4-(4-(4-(3-trifluoromethylphenyl)piperazin-1-yl)butyl)phenyl ]pyrrolidin-2-one.

Sources & evidence

ORD record
ord-ac270582da89426e8a9b3ba0c39e4dad
Source dataset
uspto-grants-1990_06
Patent number
US04931443

Reaction notes

Loading…