Ethylamine → HCID 23048794, compound

HRID 2106652Notes

Reaction equation

HRID 2106652 reaction equation
O=[C:2]([C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][N:17]2[CH2:22][CH2:21][N:20]([C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[CH:24]=3)[CH2:19][CH2:18]2)=[CH:10][CH:9]=1)[CH2:3][CH2:4][C:5](O)=[O:6].[CH2:30]([NH2:32])[CH3:31]>>[CH2:30]([N:32]1[CH:2]([C:8]2[CH:9]=[CH:10][C:11]([CH2:14][CH2:15][CH2:16][N:17]3[CH2:22][CH2:21][N:20]([C:23]4[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[CH:24]=4)[CH2:19][CH2:18]3)=[CH:12][CH:13]=2)[CH2:3][CH2:4][C:5]1=[O:6])[CH3:31]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 23048840HCID 23048840, compound

Product 1

HCID 23048794HCID 23048794, compound

Procedure

4-Oxo-4-[4-(3-(4-(3-methylphenyl)piperazin-1-yl)propyl)phenyl]butyric acid and ethylamine are reacted together to give N-ethyl-5-[4-(3-(4-(3-methylphenyl)piperazin-1-yl)propyl)phenyl]pyrrolidin-2-one.

Sources & evidence

ORD record
ord-055ee95c388c432ca15952c456104bb9
Source dataset
uspto-grants-1990_06
Patent number
US04931443

Reaction notes

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