Aniline → HCID 23048792, compound

HRID 2106654Notes

Reaction equation

HRID 2106654 reaction equation
O=[C:2]([C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][N:17]2[CH2:22][CH2:21][N:20]([C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[CH:24]=3)[CH2:19][CH2:18]2)=[CH:10][CH:9]=1)[CH2:3][CH2:4][C:5](O)=[O:6].[NH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[C:31]1([N:30]2[CH:2]([C:8]3[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][N:17]4[CH2:18][CH2:19][N:20]([C:23]5[CH:28]=[CH:27][CH:26]=[C:25]([CH3:29])[CH:24]=5)[CH2:21][CH2:22]4)=[CH:10][CH:9]=3)[CH2:3][CH2:4][C:5]2=[O:6])[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 23048840HCID 23048840, compound

Product 1

HCID 23048792HCID 23048792, compound

Procedure

4-Oxo-4-[4-(3-(4-(3-methylphenyl)piperazin-1-yl)propyl)phenyl]butyric acid and aniline are reacted together to give N-phenyl-5-[4-(3-(4-(3-methylphenyl)piperazin-1-yl)propyl)phenyl]pyrrolidin-2-one.

Sources & evidence

ORD record
ord-89be794fa8874e2abed6dc93c0cb0e81
Source dataset
uspto-grants-1990_06
Patent number
US04931443

Reaction notes

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