1-(3-Chlorophenyl)piperazine → HCID 23048839, compound

HRID 2106655Notes

Reaction equation

HRID 2106655 reaction equation
C1(C)C=CC(S(O[CH2:11][CH2:12][CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][C:18]([CH:21]3[NH:25][C:24](=[O:26])[CH2:23][CH2:22]3)=[CH:17][CH:16]=2)(=O)=O)=CC=1.[Cl:28][C:29]1[CH:30]=[C:31]([N:35]2[CH2:40][CH2:39][NH:38][CH2:37][CH2:36]2)[CH:32]=[CH:33][CH:34]=1>>[Cl:28][C:29]1[CH:30]=[C:31]([N:35]2[CH2:40][CH2:39][N:38]([CH2:11][CH2:12][CH2:13][CH2:14][C:15]3[CH:16]=[CH:17][C:18]([CH:21]4[NH:25][C:24](=[O:26])[CH2:23][CH2:22]4)=[CH:19][CH:20]=3)[CH2:37][CH2:36]2)[CH:32]=[CH:33][CH:34]=1

Participants

3

Reactant 2

HCID 13551-(3-Chlorophenyl)piperazineHCID 23048816HCID 23048816, compound

Product 1

HCID 23048839HCID 23048839, compound

Procedure

5-[4-(4-(p-Toluenesulfonyloxy)butyl)phenyl]pyrrolidin-2-one and 1-(3-chlorophenyl)piperazine are reacted together to give 5-[4-(4-(4-(3-chlorophenyl)piperazin-1-yl)butyl)phenyl]-pyrrolidin-2-one.

Sources & evidence

ORD record
ord-53ac6fe9e8e24a479ea66fce84d653e1
Source dataset
uspto-grants-1990_06
Patent number
US04931443

Reaction notes

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