1-(m-Tolyl)piperazine → HCID 23048819, compound

HRID 2106657Notes

Reaction equation

HRID 2106657 reaction equation
[CH2:1]([N:3]([CH2:6][CH2:7][N:8]1[CH:12]([C:13]2[CH:18]=[CH:17][C:16]([CH2:19][CH2:20][CH2:21][CH2:22]OS(C3C=CC(C)=CC=3)(=O)=O)=[CH:15][CH:14]=2)[CH2:11][CH2:10][C:9]1=[O:34])[CH2:4][CH3:5])[CH3:2].[CH3:35][C:36]1[CH:37]=[C:38]([N:42]2[CH2:47][CH2:46][NH:45][CH2:44][CH2:43]2)[CH:39]=[CH:40][CH:41]=1>>[CH2:4]([N:3]([CH2:6][CH2:7][N:8]1[CH:12]([C:13]2[CH:14]=[CH:15][C:16]([CH2:19][CH2:20][CH2:21][CH2:22][N:45]3[CH2:46][CH2:47][N:42]([C:38]4[CH:39]=[CH:40][CH:41]=[C:36]([CH3:35])[CH:37]=4)[CH2:43][CH2:44]3)=[CH:17][CH:18]=2)[CH2:11][CH2:10][C:9]1=[O:34])[CH2:1][CH3:2])[CH3:5]

Participants

3

Reactant 2

HCID 831111-(m-Tolyl)piperazineHCID 23048815HCID 23048815, compound

Product 1

HCID 23048819HCID 23048819, compound

Procedure

N-(2-(N,N-diethylamino)ethyl)-5-[4-(4-(p-toluenesulfonyloxy)butyl)phenyl]pyrrolidin-2-one and 1-(3-methylphenyl)piperazine are reacted together to give N-(2-(N,N-diethylamino)ethyl)-5-[4-(4-(4-(3-methylphenyl)piperazin-1-yl)butyl)phenyl]pyrrolidin-2-one.

Sources & evidence

ORD record
ord-3dec1bded96741d283bc023d8519aa16
Source dataset
uspto-grants-1990_06
Patent number
US04931443

Reaction notes

Loading…