Potassium Carbonate → HCID 54468434, compound

Participants

Reaction Steps

1-Bromo-4-(2-furanyl)-4-phenylbut-3-ene (0.23 g, 0.83 mmol) was dissolved in anhydrous acetone (10 ml) and dried potassium carbonate (0.46 g, 3.32 mmol) was added, followed by ethyl nipecotate (0.16 g, 1 mmol). The suspension was stirred at room temperature for 9 days, filtered and evaporated to a residue. The residue was purified by column chromatography on silica gel (Merck Art 9385), eluting with heptane/tetrahydrofuran (7:3), to provide the title ester (140 mg, 47%) as an oil. T.l.c. rf=0.36 (SiO2, heptane/THF (7:3)).

Provenance & Evidence