反应详情

Prepared analogously to Example 1 from 11-(chlorocarbonyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 3-[4-(1-pyrrolidinyl)butyl]piperidine in a yield of 50% of theory. Colourless crystals, m.p. 153°-156° C. (ethyl acetate/diethylether 1/1, v/v), Rf 0.25 (Merck DC ready made TLC plates, silica gel 60 F254 ; eluant: dichloromethane/methanol/conc. ammonia 90/10/1, v/v/v).