11-(chlorocarbonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one → 11-[[3-[3-(Diethylamino)propyl]-1-piperidinyl]carbonyl]-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	11-(chlorocarbonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one	HCID 14209983	—
Edukt	3-[3-(Diethylamino)propyl]piperidine	HCID 15057301	—
Lösungsmittel	Acetonitrile	HCID 6342	—
Produkt	11-[[3-[3-(Diethylamino)propyl]-1-piperidinyl]carbonyl]-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one	HCID 14369672	38%

Reaktionsschritte

Prepared analogously to Example 4 from 11-(chlorocarbonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one and 3-[3-(diethylamino)propyl]piperidine in a yield of 38% of theory. Colourless crystals, m.p. 123°-125° C. (acetonitrile).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US04931436
Quelldatensatz	uspto-grants-1990_06
ORD ID	ord-45dce7de650a468f93e97314c5d77c3f
Quellennotiz	uspto-grants-1990_06