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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2106704Generated: October 31, 2026

4-Piperidinebutanamine, N,N-diethyl- → 11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]carbonyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

https://huagongshe.com/reaction/2106704

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Piperidinebutanamine, N,N-diethyl-HCID 10081918—
Reactant11-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-oneHCID 11043962—
Product11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]carbonyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-oneHCID 1436966062%

Reaction Steps

Prepared analogously to Example 4 from 11-(chlorocarbonyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 4-[4-(diethylamino)butyl]piperidine in a yield of 62% of theory. Colourless crystals, m.p. 126°-127° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04931436
Source datasetuspto-grants-1990_06
ORD IDord-4e1e9571772a41bc9a03286df3721fb6
Source noteuspto-grants-1990_06