Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2106714Generated: October 31, 2026

Hydrochloric Acid → 11-[[4-[2-[2-(Diethylamino)ethoxy]ethyl]-1-piperidinyl]carbonyl]-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one

https://huagongshe.com/reaction/2106714

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant11-(chlorocarbonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-oneHCID 14209983—
Reactant4-[2-[2-(Diethylamino)ethoxy]ethyl]piperidineHCID 15057325—
Product11-[[4-[2-[2-(Diethylamino)ethoxy]ethyl]-1-piperidinyl]carbonyl]-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-oneHCID 1505734383%

Reaction Steps

Prepared analogously to Example 4 from 11-(chlorocarbonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one and 4-[2-[2-(diethylamino)ethoxy]ethyl]piperidine in a yield of 83% of theory. The colourless hydrochloride melted at 148°-150° C. (ethyl acetate).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04931436
Source datasetuspto-grants-1990_06
ORD IDord-3e1371ffb92c4dc98c6652f949f3970e
Source noteuspto-grants-1990_06