HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 23048744, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-chlorocarbonyl-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one | HCID 14209980 | — |
| Reactant | 2-[2-(1-Piperidinyl)ethyl]morpholine | HCID 15057327 | — |
| Product | HCID 23048744 | HCID 23048744 | 74% |
Reaction Steps
Prepared analogously to Example 4 from 4-(chlorocarbonyl)-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one and 2-[2-(1-piperidinyl)ethyl]morpholine in a yield of 74% of theory. Rf 0.48 (conditions as in Example 58). The colourless hydrochloride melted at 254°-256° C. (D.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04931436 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-faa9d0f4e3524616b89e4f06f9d1a53f |
| Source note | uspto-grants-1990_06 |