Butyl bromide → HCID 23048843, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 40 parts of 2-(4-nitrophenyl)-1,2,4-triazine-3,5-(2H,4H)-dione, 25.7 parts of 1-bromobutane, 26.25 parts of potassium carbonate and 720 parts of N,N-dimethylformamide was stirred overnight at 45° C. The reaction mixture was poured into 2000 parts of ice water. The precipitated product was filtered off, washed with water and 2,2'-oxybispropane and stirred in methanol. The product was filtered off and dried in vacuo at 70° C., yielding 33.9 parts (68.6%) of 4-butyl-2-(4-nitrophenyl)-1,2,4-triazine-3,5(2H,4H)-dione (int. 27).

Provenance & Evidence