HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2106770Generated: October 30, 2026
Dimethyl Sulfoxide → 1-(4-Nitrophenyl)4-propyl-5-tetrazolone
https://huagongshe.com/reaction/2106770
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | p-Fluoronitrobenzene | HCID 9590 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1,4-dihydro-1-propyl-5H-tetrazol-5-one | HCID 135829348 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-(4-Nitrophenyl)4-propyl-5-tetrazolone | HCID 15125485 | 74% |
Reaction Steps
A mixture of 38 parts of 1-fluoro-4-nitrobenzene, 32 parts of 1,4-dihydro-1-propyl-5H-tetrazol-5-one, 14 parts of sodium carbonate and 200 parts of dimethyl sulfoxide was stirred and heated for 4 hours at 120° C. The reaction mixture was cooled and poured into water. The precipitated product was filtered off and crystallized from 2-propanol, yielding 46 parts (74%) of 1,4-dihydro-1-(4-nitrophenyl)-4-propyl-5H-tetrazol-5-one; mp. 91.1° C. (int. 31).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04931444 |
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| Source dataset | uspto-grants-1990_06 |
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| ORD ID | ord-4f53aaae98fe4aaba71ddb0a1aca653f |
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| Source note | uspto-grants-1990_06 |
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