Triethylamine → HCID 23049304, compound

Participants

Reaction Steps

7-phenylhept-2E-en-6-ynoic acid (100 mg) was converted to the acid chloride as described in Example 2(a). The acid chloride was treated with triethylamine (73 ul) and 3-methoxybenzylamine (77 ul) in ether (2 ml). The product was recovered as described in Example 1 and purified by chromatography on silica, eluting with ether:hexane (1:1) to yield N-(3-methoxybenzyl)-7-phenylhept-2E-en-6-ynamide as a colourless solid, m.p. 96.3°-98.9°.

Provenance & Evidence