Ethanol → HCID 70372312, compound

HRID 2106869Notes

Reaction equation

HRID 2106869 reaction equation
[CH3:1]/[C:2](=[CH:8]\[CH2:9][CH2:10][C:11]#[C:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)/[C:3]([O:5]CC)=[O:4].C(O)C.[OH-].[K+]>O>[CH3:1]/[C:2](=[CH:8]\[CH2:9][CH2:10][C:11]#[C:12][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1)/[C:3]([OH:5])=[O:4]

Participants

5

Reactant 3

HCID 702EthanolHCID 14797Potassium HydroxideHCID 70372346HCID 70372346, compound

Product 1

HCID 70372312HCID 70372312, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The ethyl 2-methyl-7-phenyl-(2E)-heptene-6-ynoate (1.0 g, 4.13 mmol), ethanol (4 ml), potassium hydroxide (1 g) and water (4 ml) were heated together under a nitrogen atmosphere at 50° C. for 2 hours. The reaction mixture was worked up as in Example 1 to give 0.84 g (95% of theory) of 2-methyl-7-phenyl-(2E)-hepten-6-ynoic acid as a colourless solid.

Sources & evidence

ORD record
ord-2d949c88833547d2b6178cd21734883d
Source dataset
uspto-grants-1990_06
Patent number
US04931469

Reaction notes

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