4-Iodoanisole → 5-(4-Methoxyphenyl)pent-4-yn-1-ol

HRID 2106874Notes

Reaction equation

[CH2:1]([OH:6])[CH2:2][CH2:3][C:4]#[CH:5].I[C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1>>[CH3:15][O:14][C:11]1[CH:12]=[CH:13][C:8]([C:5]#[C:4][CH2:3][CH2:2][CH2:1][OH:6])=[CH:9][CH:10]=1

Participants

Reactant 2

HCID 696764-Iodoanisole

HCID 793464-Pentyn-1-ol

Product 1

HCID 115501385-(4-Methoxyphenyl)pent-4-yn-1-ol

Procedure

5-(4'-methoxyphenyl)-4-pentyn-1-ol was prepared from 4-pentyn-1-ol and 4-iodoanisole using the same method as in Example 15 to give 1.55 g (70% of theory) of product.

Workup

customto give 1.55 g (70% of theory) of product

Sources & evidence

ORD record: ord-fee3ba58bd524bbca54bad9437288df9
Source dataset: uspto-grants-1990_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04931469

Reaction notes

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