4-Pentyn-1-ol → HCID 23049351, compound

HRID 2106880Notes

Reaction equation

HRID 2106880 reaction equation
C(O)CCC#C.[Cl:7][C:8]1[CH:9]=[C:10]([C:15]#[C:16][CH2:17][CH2:18][CH:19]=[O:20])[CH:11]=[CH:12][C:13]=1[F:14]>>[Cl:7][C:8]1[CH:9]=[C:10]([C:15]#[C:16][CH2:17][CH2:18][CH2:19][OH:20])[CH:11]=[CH:12][C:13]=1[F:14]

Participants

3

Reactant 2

HCID 793464-Pentyn-1-olHCID 23049349HCID 23049349, compound

Product 1

HCID 23049351HCID 23049351, compound

Procedure

5-(3'-chloro-4'-fluorophenyl)-4-pentyn-1-ol was prepared from 4-pentyn-1-ol and 3'-chloro-4'-fluoro-iodobenzene as in Example 15 and converted into 5-(3'-chloro-4'-fluorophenyl)-4-pentyn-1-al as in Example 9.

Sources & evidence

ORD record
ord-43ebe198b5bf446a965b991e5feaa092
Source dataset
uspto-grants-1990_06
Patent number
US04931469

Reaction notes

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