Sodium Bisulfate → HCID 14473226, compound

Participants

Reaction Steps

10 g of 3-methoxy-4-butylthiophene, prepared from 3-bromo-4-butylthiophene by reaction with sodium methylate in methanol with catalysis by CuO, b.p. 54° C./0.26 mbar, were dissolved as in Example 14 in 50 cm3 of 1-hexanol and 30 ml of toluene, and 1 g of NaHSO4 was added. After distilling off 6 cm3 of azeotrope, the batch was worked up as in Example 14. Yield 8.5 g of 3-hexyloxy-4-butylthiophene of b.p. 112° to 116° C./0.26 mbar, which corresponds to 60% of theory.

Provenance & Evidence