HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzenesulfonamide → 1-(4'-Nitrobenzenesulfonyl)-3-methoxycarbonyl urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzenesulfonamide | HCID 22784 | — |
| Reactant | Methyl isocyanatoformate | HCID 4156749 | — |
| Catalyst | Pyridine | HCID 1049 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(4'-Nitrobenzenesulfonyl)-3-methoxycarbonyl urea | HCID 23049624 | 79.1% |
Reaction Steps
To 4-nitrobenzenesulfonamide (2.1 grams, 0.01 mole) in 100 milliliters dry toluene was added 1.2 grams (0.012 mole) methoxycarbonyl isocyanate. Three drops of pyridine were added. The mixture was refluxed for four hours. After cooling the precipitate was filtered off and washed with toluene. The solid material was dried. There was obtained 2.4 grams of the title compound, m.p. 150°-158° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04931580 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-bc220545435a4a8ba84aa91d0580c284 |
| Source note | uspto-grants-1990_06 |