HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2106942Generated: October 31, 2026
Benzyl mercaptan → Methyl 2-benzylmercapto-3-nitrobenzoate
https://huagongshe.com/reaction/2106942
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzyl mercaptan | HCID 7509 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2-chloro-3-nitrobenzoate | HCID 10751184 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 2-benzylmercapto-3-nitrobenzoate | HCID 54046874 | — |
Reaction Steps
45.4 g (0.21 mol) of 2-chloro-3-nitrobenzoic acid methyl ester and 24.8 ml (0.21 mol) of benzyl mercaptan are dissolved in 420 ml of dimethylformamide, and then 29.2 g (0.21 mol) of potassium carbonate are added and the batch is stirred for 8 hours at 80° C. It is then poured onto ice/water and extracted twice with ethyl acetate. The extracts are washed with water, dried over magnesium sulfate and concentrated by evaporation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04931581 |
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| Source dataset | uspto-grants-1990_06 |
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| ORD ID | ord-172f3b8efa1448898a81f9a087d53af0 |
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| Source note | uspto-grants-1990_06 |
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