HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2107009Generated: October 27, 2026
Benzaldehyde → Methyl 2-hydroxy-5-benzylideneaminobenzoate
https://huagongshe.com/reaction/2107009
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Methyl 5-amino-2-hydroxybenzoate | HCID 135127 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Methyl 2-hydroxy-5-benzylideneaminobenzoate | HCID 23047222 | 69% |
Reaction Steps
Methyl 2-hydroxy-5-aminobenzoate (43.6 g, 0.261 mole) was dissolved in benzaldehyde (26.6 ml, 0.26 mole) by heating to 100° C. for 10 minutes and cooled with ice-water after which 95% ethanol (40 ml) was added, and the resulting crystalline material was isolated by filtration. The product was recrystallized from 96% ethanol to give the title compound (45.6 g, 69%), m.p. 58°-59° C. Found (Calc. for C15H13NO3) C 70.60 (70.58), H 5.06 (5.10), N 5.50 (5.49).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04933330 |
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| Source dataset | uspto-grants-1990_06 |
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| ORD ID | ord-5c0ab7e86b09447fa2774747c2082aad |
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| Source note | uspto-grants-1990_06 |
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