Hydrazine hydrate (1:1) → HCID 14852300, compound

Participants

Reaction Steps

The product of Example A (33.0 g, 100.6 mmol) was refluxed in ethanol (1 L) in the presence of hydrazine hydrate (20.2 g, 402.4 mmol) for 4.5 hours. The reaction mixture was cooled and filtered. The solid was washed with ethanol. The filtrate and solid were combined and stripped at reduced pressure. The resulting mass was repeatedly triturated with diethyl ether. The ether fractions were combined, filtered, and stripped at reduced pressure to give the title compound as a yellow oil.

Provenance & Evidence