Ammonia → HCID 86744021, compound

HRID 2107157Notes

Reaction equation

HRID 2107157 reaction equation
[C:1]1([CH3:26])[CH:6]=[CH:5][C:4]([S:7]([NH:10][C:11](=[O:25])[NH:12][C:13]2[S:14][CH:15]=[C:16]([C:18](=O)[C:19]([O:21][CH2:22][CH3:23])=[O:20])[N:17]=2)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[S:27]1[CH2:33][C:31](=[O:32])[N:30]([CH2:34][C:35]([OH:37])=[O:36])[C:28]1=[S:29].[Cl-].[NH4+].N>C(O)C>[OH2:8].[CH2:22]([O:21][C:19]([C:18](=[C:33]1[S:27][C:28](=[S:29])[N:30]([CH2:34][C:35]([OH:37])=[O:36])[C:31]1=[O:32])[C:16]1[N:17]=[C:13]([NH:12][C:11]([NH:10][S:7]([C:4]2[CH:5]=[CH:6][C:1]([CH3:26])=[CH:2][CH:3]=2)(=[O:9])=[O:8])=[O:25])[S:14][CH:15]=1)=[O:20])[CH3:23]

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053512HCID 15053512, compound

Product 1

HCID 86744021HCID 86744021, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared from 4 g of ethyl 2-(3-p-toluenesulfonylureido)thiazol-4-ylglyoxylate, 2 g of rhodanine-3-acetic acid, 1 g of ammonium chloride, 1 ml of 28% v/v aqueous ammonia and 10 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-6e2a53c29acd4d958a39298d3fa1616b
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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