Ammonia → HCID 54532528, compound

HRID 2107158Notes

Reaction equation

HRID 2107158 reaction equation
[C:1]([NH:9][C:10]1[S:11][CH:12]=[C:13]([C:15](=O)[C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:14]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:22]1[CH2:28][C:26](=[O:27])[N:25]([CH2:29][C:30]([OH:32])=[O:31])[C:23]1=[S:24].[Cl-].[NH4+].N>C(O)C>[C:1]([NH:9][C:10]1[S:11][CH:12]=[C:13]([C:15](=[C:28]2[S:22][C:23](=[S:24])[N:25]([CH2:29][C:30]([OH:32])=[O:31])[C:26]2=[O:27])[C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:14]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053526HCID 15053526, compound

Product 1

HCID 54532528HCID 54532528, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared from 3.04 g of ethyl 2-benzamidothiazol-4-ylglyoxylate, 1.91 g of rhodanine-3-acetic acid, 1 g of ammonium chloride, 1 ml of 28% v/v aqueous ammonia and 20 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-3bcdd72ba6a6442a887cadbc5b78c293
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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