Piperidine → HCID 74015737, Verbindung

HRID 2107165Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2107165
[C:1]([NH:20][C:21]1[S:22][CH:23]=[C:24]([CH:26]=O)[N:25]=1)([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:28]1[CH2:34][C:32](=[O:33])[N:31]([CH2:35][C:36]([OH:38])=[O:37])[C:29]1=[S:30].[NH:39]1[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]1>C(O)C>[C:1]([NH:20][C:21]1[S:22][CH:23]=[C:24]([CH:26]=[C:34]2[S:28][C:29](=[S:30])[N:31]([CH2:35][C:36]([O-:38])=[O:37])[C:32]2=[O:33])[N:25]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)([C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2+:39]1[CH2:44][CH2:43][CH2:42][CH2:41][CH2:40]1

Komponenten

5

Edukt 3

HCID 8082PiperidineHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 150535692-(Tritylamino)thiazole-4-carbaldehyde

Produkt 1

HCID 74015737HCID 74015737, VerbindungAusbeute 101,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture comprising 2.5 g of 2-tritylaminothiazole-4-carbaldehyde, 0.81 g of rhodanine-3-acetic acid, 1.1 g of piperidine and 25 ml of ethanol was stirred at room temperature for 7 hours. The crystalline product which precipitated out was collected by filtration and washed with methanol, to obtain 2.7 g of the desired compound as a yellowish-brown powder.

Aufarbeitung

  1. customThe crystalline product which precipitated out
  2. filtrationwas collected by filtration
  3. washwashed with methanol

Quellen und Nachweise

ORD-Eintrag
ord-41f04f5b11a54eadae53e166c78e148a
Quelldatensatz
uspto-grants-1990_06
Patentnummer
US04933355

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