Ammonia → HCID 54114429, compound

HRID 2107175Notes

Reaction equation

HRID 2107175 reaction equation
[C:1]([NH:9][C:10](=[S:24])[NH:11][C:12]1[S:13][CH:14]=[C:15]([C:17](=O)[C:18]([O:20][CH2:21][CH3:22])=[O:19])[N:16]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:25]1[CH2:31][C:29](=[O:30])[N:28]([CH2:32][C:33]([OH:35])=[O:34])[C:26]1=[S:27].[Cl-].[NH4+].N>C(O)C>[C:1]([NH:9][C:10](=[S:24])[NH:11][C:12]1[S:13][CH:14]=[C:15]([C:17](=[C:31]2[S:25][C:26](=[S:27])[N:28]([CH2:32][C:33]([OH:35])=[O:34])[C:29]2=[O:30])[C:18]([O:20][CH2:21][CH3:22])=[O:19])[N:16]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053515HCID 15053515, compound

Product 1

HCID 54114429HCID 54114429, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction described in Example 1 was repeated, but using 1.5 g of ethyl 2-(3-benzoylthioureido)thiazol-4-ylglyoxylate, 0.79 g of rhodanine-3-acetic acid, 0.1 g of ammonium chloride, 0.4 ml of 28% v/v aqueous ammonia, and 20 ml of ethanol, giving the title compound as a yellow powder.

Sources & evidence

ORD record
ord-b62a9c6705fa4939ab81fc81e1914587
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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