Ammonia → HCID 54214111, compound

HRID 2107180Notes

Reaction equation

HRID 2107180 reaction equation
[C:1]1([NH:7][C:8](=[O:24])[NH:9][C:10]2[S:11][CH:12]=[C:13]([C:15](=O)[C:16]([O:18][CH2:19][CH:20]([CH3:22])[CH3:21])=[O:17])[N:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[S:25]1[CH2:31][C:29](=[O:30])[N:28]([CH2:32][C:33]([OH:35])=[O:34])[C:26]1=[S:27].[Cl-].[NH4+].N>C(O)C>[CH2:19]([O:18][C:16]([C:15](=[C:31]1[S:25][C:26](=[S:27])[N:28]([CH2:32][C:33]([OH:35])=[O:34])[C:29]1=[O:30])[C:13]1[N:14]=[C:10]([NH:9][C:8]([NH:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[O:24])[S:11][CH:12]=1)=[O:17])[CH:20]([CH3:22])[CH3:21]

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053516HCID 15053516, compound

Product 1

HCID 54214111HCID 54214111, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared from 160 mg of isobutyl 2-(3-phenylureido)thiazol-4-ylglyoxylate, 90 mg of rhodanine-3-acetic acid, 50 mg of ammonium chloride, 0.05 ml of 28% v/v aqueous ammonia and 2 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-3430c8a4a6c84e7fa7e912cf1363df18
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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