Ammonia → HCID 53707131, compound

HRID 2107186Notes

Reaction equation

HRID 2107186 reaction equation
[C:1]1([CH3:23])[CH:6]=[CH:5][C:4]([NH:7][C:8](=[O:22])[NH:9][C:10]2[S:11][CH:12]=[C:13]([C:15](=O)[C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:14]=2)=[CH:3][CH:2]=1.[S:24]1[CH2:30][C:28](=[O:29])[N:27]([CH2:31][C:32]([OH:34])=[O:33])[C:25]1=[S:26].[Cl-].[NH4+].N>C(O)C>[CH2:19]([O:18][C:16]([C:15](=[C:30]1[S:24][C:25](=[S:26])[N:27]([CH2:31][C:32]([OH:34])=[O:33])[C:28]1=[O:29])[C:13]1[N:14]=[C:10]([NH:9][C:8]([NH:7][C:4]2[CH:5]=[CH:6][C:1]([CH3:23])=[CH:2][CH:3]=2)=[O:22])[S:11][CH:12]=1)=[O:17])[CH3:20]

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053504HCID 15053504, compound

Product 1

HCID 53707131HCID 53707131, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared using 4.8 g of ethyl 2-(3-p-tolylureido)thiazol-4-ylglyoxylate, 2.5 g of rhodanine-3-acetic acid, 1.5 g of ammonium chloride, 1.5 ml of 20% v/v aqueous ammonia and 50 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-44ac5fa6a02f47bba7c69e58e50b8420
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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